Sleep. 2: pathophysiology of obstructive sleep apnoea/hypopnoea syndrome.
نویسندگان
چکیده
The pathogenesis of airway obstruction in patients with obstructive sleep apnoea/hypopnoea syndrome is reviewed. The primary defect is probably an anatomically small or collapsible pharyngeal airway, in combination with a sleep induced fall in upper airway muscle activity.
منابع مشابه
Obstructive Sleep Apnoea Warning Signs of the Sleepy Snorer
Seven names 1 condition! The definition of sleep apnoea can be confusing because it is described in research literature under many guises: Obstructive Sleep apnoea (OSA) Sleep Apnoea (SA) Obstructive Sleep Apnoea Syndrome (OSAS) Sleep Apnoea/Hypopnoea Syndrome (SAHS) Obstructive Sleep Apnoea/Hypopnoea Syndrome (OSA/H) and of late, a new condition has been introduced Upper Airway Resistance Synd...
متن کاملTumour necrosis factor-α/interleukin-10 ratio in patients with obstructive sleep apnoea hypopnoea syndrome.
OBJECTIVE To explore the significance of the tumour necrosis factor-α/interleukin-10 ratio and the effect of continuous positive airway pressure in patients with different degrees of obstructive sleep apnoea hypopnoea syndrome severity. METHOD This study comprised 135 patients with obstructive sleep apnoea hypopnoea syndrome and 94 control subjects. RESULTS Tumour necrosis factor-α and tumo...
متن کاملSleep. 1: Obstructive sleep apnoea/hypopnoea syndrome: definitions, epidemiology, and natural history.
Arguments over the definition of obstructive sleep apnoea/hypopnoea syndrome (OSAHS) have still not been satisfactorily resolved. As a result, robust estimates of the prevalence of OSAHS are not possible. New approaches are needed to identify those who have "CPAP responsive" disease, enabling more accurate estimates to be made of the prevalence of the sleep apnoea syndrome in the community.
متن کاملERS TASK FORCE Public health and medicolegal implications of sleep apnoea
Definition of sleep apnoea syndrome . . . . . . . . .1594 Epidemiology and clinical aspects . . . . . . . . . . .1595 Sleep apnoea in the young and elderly . . . . . 1596 Morbidity and mortality related to sleep apnoea syndrome . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1597 Impact of treatment of obstructive sleep apnoea/ hypopnoea on associated cardiovascular morbidity . . . . . ...
متن کاملCase reports Transtracheal air in the treatment of obstructive sleep apnoea hypopnoea syndrome
A 49 year old woman with typical obstructive sleep apnoea hypopnoea syndrome underwent an unsuccessful trial with continuous positive airway pressure (CPAP) followed by uvulopalatopharyngoplasty with septorhinoplasty, treatment with protriptyline, and a second CPAP trial that was abandoned. Transtracheal air was then given and normalised sleep and breathing at a flow rate of 5 l/min. A sustaine...
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عنوان ژورنال:
- Thorax
دوره 59 2 شماره
صفحات -
تاریخ انتشار 2004